University of Texas at Austin

Cross-
Cutting
Research Area

Computational Medicine

Modeling the Individuality of Health and Disease for More Accurate Decision Making

A Patient-Centric Approach - Providing Diagnosis and Treatment Tailored to Each Individual

Through its advanced mathematical and simulation approaches, computational medicine can build models of human physiology with unprecedented accuracy - from the cellular level to the entire body.

An Overview: Computational Medicine

What is Computational Medicine?

Computational Medicine uses advanced mathematical and simulation approaches to model the human body in a spectrum ranging from the molecule to the organ to the entire body and ultimately, to the health care system. To accurately represent such complex systems, the models need to capture the individuality of health and disease for accurate decision making at all levels. Ranging from the patient to the policy, these require state-of-the-art computational capabilities to make them a reality. The models can be theory–, knowledge–, or data–driven, or any combination of the three.

Current research areas

Research is multifaceted, ranging from foundational advances in theory, methods and algorithms, to real-world impact in societal grand challenge problems.

medical imaging

Medical imaging

molecular biophysics

Molecular biophysics

cardiovascular-science

Cardiovascular Science

neuroscience

Neuroscience

oncology

Oncology

Genomic dataset analysis

Genomic dataset analysis

Working with partners

The University of Texas MD Anderson Cancer Center, Oden Institute’s Center for Computational Oncology, led by Dr. Tom Yankeelov, and TACC are working together to find new cancer treatments through integrating oncological data with mechanism-based modeling techniques. MD Anderson is one of the world's largest and most respected centers devoted exclusively to cancer patient care, research, education and prevention. Read more about our collaborations.

The Willerson Center for Cardiovascular Modeling and Simulation, led by Dr. Michael Sacks, at Oden Institute has been a long-standing partner of the Texas Heart institute (THI). The THI is recognized internationally for research programs in cardiology, cardiovascular surgery, regenerative medicine and pathology. The partnership with the Oden Institute is underpinned by research to advance computational modeling of the cardiovascular system with a view to providing tailored care for each individual patient suffering from heart disease — the number one cause of death worldwide.

Centers and Groups

To learn more about projects and people in Computational Medicine, explore the centers and groups with research activities in this cross-cutting research area.

Center for Computational Oncology

Willerson Center for Cardiovascular Modeling and Simulation

Center for Computational Life Sciences and Biology

News in brief

Collaboration on Data and Computational Sciences Announces 2021-2022 Projects to Advance Cancer Breakthroughs

News

Nov. 10, 2021

Collaboration on Data and Computational Sciences Announces 2021-2022 Projects to Advance Cancer Breakthroughs

  • Second round of funded projects announced in cooperative research and educational program in Oncological Data and Computational Sciences.
  • Latest projects include new ways for identifying, characterizing and treating prostate cancer, blood-related cancer, liver cancer and skin cancer.

Read more

New UT research predicts effectiveness of breast cancer treatments — here’s how

Media Coverage

Oct. 14, 2021

New UT research predicts effectiveness of breast cancer treatments — here’s how

Read more at kxan

Technique Predicts Tumor Response to Cancer Therapy

News

Oct. 5, 2021

Technique Predicts Tumor Response to Cancer Therapy

  • Public/private collaboration led by UT Austin uses new mathematical modeling technique to predict response of tumors in breast cancer patients to first-line therapies
  • Research is “culmination of several years of work in a public-private partnership”  including Oden Institute, BME, Dell Med, Texas Oncology, Dell Seton Medical Center and Austin Radiological Association.

Read more

How surgeons are using new technology to get inside brain cancer and destroy it

Media Coverage

Sept. 22, 2021

How surgeons are using new technology to get inside brain cancer and destroy it

Read more at wqad

Oden Institute Joins the Forty for 40 Party

News

Sept. 22, 2021

Oden Institute Joins the Forty for 40 Party

  • First time Oden Institute participates in 40 hours for the Forty Acres  
  • Annual UT Austin fundraising event now in its ninth year

Read more at utexas

Introducing The 2021 Fellowship…

Feature

Aug. 31, 2021

Introducing The 2021 Fellowship…

  • 2021 Peter O'Donnell, Jr. Postdoctoral Fellows bring variety of new skillsets and diverse research interests
  • Scope of projects range from computational modeling at atomic scale to development of tsunami simulation techniques

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Thomas Hughes Honored by Japan Association for Computational Mechanics

News

Aug. 30, 2021

Thomas Hughes Honored by Japan Association for Computational Mechanics

  • Peter O'Donnell, Jr. Chair in Computational and Applied Mathematics inducted with Tayfun Tezduyar from Rice University
  • Tezduyar and Hughes first non-Japanese so honored by JACM

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Shashank Subramanian Awarded BGCE Student Paper Prize at SIAM CSE 2021

News

March 19, 2021

Shashank Subramanian Awarded BGCE Student Paper Prize at SIAM CSE 2021

  • 27-year-old PhD student working at the Center for Computational Oncology with Dr. George Biros.
  • Subramanian was awarded BGCE Student Paper Prize for paper entitled, “A scalable inversion framework for brain tumor growth models in personalized medicine.”

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Modeling The Fate Of A Blood Clot

News

March 10, 2021

Modeling The Fate Of A Blood Clot

  • Rausch to work on five year proposal
  • 'Towards a Fundamental Understanding of Why Thrombus Dissolves, Persists, or Breaks Off'

Read more

Computational Medicine — Moving from Uncertainty to Precision

News

Feb. 12, 2021

Computational Medicine — Moving from Uncertainty to Precision

  • Collaboration between Dell Med, Oden Institute, TACC, industry, government establishes Texas as computational medicine leader
  • Interdisciplinary research group provides a unique combination of resources

Read more at tacc.utexas

UT Austin and MD Anderson Collaboration to End Cancer Welcomed Enthusiastically by State and Federal Stakeholders

News

Nov. 3, 2020

UT Austin and MD Anderson Collaboration to End Cancer Welcomed Enthusiastically by State and Federal Stakeholders

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UT Austin, MD Anderson Announce First Collaborative Projects in United Fight to End Cancer

News

Oct. 19, 2020

UT Austin, MD Anderson Announce First Collaborative Projects in United Fight to End Cancer

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Oden Institute Welcomes Two New Faculty to UT Austin

News

Sept. 17, 2020

Oden Institute Welcomes Two New Faculty to UT Austin

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Computational Modeling Techniques Enable Unprecedented Visualizations of Heart Valve Implant Behavior

News

July 31, 2020

Computational Modeling Techniques Enable Unprecedented Visualizations of Heart Valve Implant Behavior

Read more