University of Texas at Austin

Cross-
Cutting
Research Area

Scientific Machine Learning

Harnessing the data through the lens of physics-based modeling

Embracing the opportunities and challenges of machine learning in complex applications across science, engineering and medicine

Existing machine learning approaches do not have the robustness, reliability, scalability, or efficiency to make them viable for grand challenge problems in science and engineering.

An Overview: Scientific Machine Learning

What is Scientific Machine Learning?

Scientific Machine Learning brings together the complementary perspectives of computational science and computer science to craft a new generation of machine learning methods for complex applications across science and engineering. In these applications, dynamics are complex and multiscale, data are sparse and expensive to acquire, decisions have high consequence, and uncertainty quantification is essential. The greatest challenges facing society — clean energy, climate change, sustainable urban infrastructure, access to clean water, personalized medicine and more — by their very nature require predictions that go well beyond the available data. Scientific machine learning achieves this by incorporating the predictive power, interpretability and domain knowledge of physics-based models.

Current research areas

Research is multifaceted, ranging from foundational advances in theory, methods and algorithms, to real-world impact in societal grand challenge problems.

medical imaging

Surrogate modeling & model reduction

molecular biophysics

Bayesian inverse problems

deep-learning

Physics-informed deep learning

data-assimilation

Data assimilation

interpretable machine learning

Interpretable machine learning

reinforcement-learning

Reinforcement learning

digital-twins

Digital twins

design

Optimal experimental design

Working with partners

The Oden Institute and The Alan Turing Institute have a memorandum of understanding to collaborate in the areas of artificial intelligence for science and engineering, computational science and engineering, scientific machine learning, and data-centric engineering. Established in 2015, The Alan Turing Institute is a high-profile, vibrant and multidisciplinary national institute, bringing together 13 leading universities from England and Scotland, making it the UK’s national institute for data science and artificial intelligence.

The Oden Institute's Center for Scientific Machine Learning has strong collaborations with Department of Energy programs, including the AEOLUS Multifaceted Mathematics Integrated Capability Center, the ARPA-E DIFFERENTIATE program for design intelligence, and the Artificial Intelligence and Decision Support for Complex Systems program. Our faculty also played a key role in the ASCR visioning report on Basic Research Needs for Scientific Machine Learning

.

News in brief

How Flooding is Informing Infectious Disease Spread

News

Feb. 27, 2023

How Flooding is Informing Infectious Disease Spread

Researchers from UT Austin have been awarded a prestigious grant from the UK’s Wellcome Trust to understand how flood and storm surge modeling could help inform infectious disease spread in Texas and beyond.

Read more

Scientists Make It One Billion Times Faster to Simulate Fusion Reactors

News

Feb. 9, 2023

Scientists Make It One Billion Times Faster to Simulate Fusion Reactors

The new simulation took only 9.4 milliseconds to run on a laptop computer, one billion times faster than a traditional model.

Read more

New Center will Develop the Mathematical and Computational Foundations of Digital Twins for Complex Energy Systems

News

Sept. 26, 2022

New Center will Develop the Mathematical and Computational Foundations of Digital Twins for Complex Energy Systems

  • Collaborative research team led by the Oden Institute establishes major new applied mathematics center for research on digital twin technology
  • M2dt Center will focus on climate and nanomanufacturing applications for digital twins 

Read more

The Peter O’Donnell Jr. Postdoctoral Research Fellows 2022-2023

Feature

Sept. 12, 2022

The Peter O’Donnell Jr. Postdoctoral Research Fellows 2022-2023

  • O’Donnell Postdoctoral Fellowship provides funding for outstanding graduates to perform high-level, computational research with exceptional faculty in an interdisciplinary environment
  • Five new postdoctoral researchers join the Oden Institute community for the 2022-2023 academic year

Read more

Karen Willcox Gives Talk on Digital Twins at TEDx 2022

Media Coverage

Sept. 1, 2022

Karen Willcox Gives Talk on Digital Twins at TEDx 2022

Read more at youtube

Advancing Interdisciplinary Data Science Research

News

Aug. 18, 2022

Advancing Interdisciplinary Data Science Research

  • Award brings together scientists and engineers from different research communities to further the theoretical foundations of data science
  • Researchers aim to combat data sets that include historical biases and elements influenced by self-interested and possibly malicious parties

Read more

Stars Shed Light on Why Stellar Populations Are So Similar in Milky Way

News

Aug. 8, 2022

Stars Shed Light on Why Stellar Populations Are So Similar in Milky Way

  • Highly detailed computational simulations help solve mystery  that has captivated astrophysicists for decades
  • Researchers discover star formation is a self-regulatory process

Read more

Oden Institute Recognizes 2021-2022 Graduates

News

June 16, 2022

Oden Institute Recognizes 2021-2022 Graduates

  • Event honored 16 students that graduated in May 2022, as well as eight other students who graduated throughout the 2021-2022 academic year
  • "Congratulations to all our PhD and Master's graduate students. Collectively, you represent an incredible set of accomplishments spanning computing, applied mathematics, statistics, machine learning, engineering, science, geoscience, and medicine."

Read more

Oden Institute Awards Ceremony 2022

Feature

May 18, 2022

Oden Institute Awards Ceremony 2022

  • Awards Ceremony finally held in-person after two years of hiatus from COVID  
  • Staff, students and faculty celebrated and recognized for their significant contributions throughout the year

Read more

Tackling Science’s Grand Challenges

News

May 18, 2022

Tackling Science’s Grand Challenges

  • Five successful applicants gain the opportunity to tackle some of society's most pressing challenges 
  • Researchers will take on a broad range of challenges - from water efficiencies, materials science at the exascale,  the development of more energy-efficient algorithms, as well as advancing individualized care for breast cancer patients     

Read more

Oden Institute is the "Silicon Valley for Computational Math, Science and Engineering" – Profile Peng Chen

Profile

May 17, 2022

Oden Institute is the "Silicon Valley for Computational Math, Science and Engineering" – Profile Peng Chen

  • The "beauty, power and practical use of computational math" inspired Research Scientist Peng Chen to pursue a career in this field.
  • The Oden Institute is the "Silicon Valley for computational math, science and engineering"

Read more

Oden Institute Director Lays Out Blueprint for Future of Digital Twins at TEDxUTAustin

Feature

March 21, 2022

Oden Institute Director Lays Out Blueprint for Future of Digital Twins at TEDxUTAustin

  • “Technological marvels” we take for granted are tangible examples of the “computational revolution” that has reshaped society over the last two decades.
  • Digital twin technology has moved beyond just aerospace engineering, to impact many other engineering disciplines as well as many other applications across science and society.

Read more

Karen Willcox Elected to National Academy of Engineering 2022

News

Feb. 11, 2022

Karen Willcox Elected to National Academy of Engineering 2022

  • Oden Institute Director joins exclusive group of just 50 engineers from UT Austin to be elected to the NAE since 1968
  • Election to academy among the highest professional distinctions bestowed upon an engineer

Read more

Oden Institute Joins the Forty for 40 Party

News

Sept. 22, 2021

Oden Institute Joins the Forty for 40 Party

  • First time Oden Institute participates in 40 hours for the Forty Acres  
  • Annual UT Austin fundraising event now in its ninth year

Read more at utexas

Researchers to Develop Digital Twin Platform for Enhanced Storm Mitigation

News

Sept. 8, 2021

Researchers to Develop Digital Twin Platform for Enhanced Storm Mitigation

  • Department of Energy funds development of computational “digital twin” framework for storm surge prediction 
  • Integration of artificial intelligence and machine learning technologies to improve accuracy 

Read more

Introducing The 2021 Fellowship…

Feature

Aug. 31, 2021

Introducing The 2021 Fellowship…

  • 2021 Peter O'Donnell, Jr. Postdoctoral Fellows bring variety of new skillsets and diverse research interests
  • Scope of projects range from computational modeling at atomic scale to development of tsunami simulation techniques

Read more

Big Compute Podcast: Karen Willcox On Digital Twins

Media Coverage

June 8, 2021

Big Compute Podcast: Karen Willcox On Digital Twins

Read more at bigcompute

Oden Institute Outstanding Dissertation Award Winner 2021 Announced

News

March 24, 2021

Oden Institute Outstanding Dissertation Award Winner 2021 Announced

  • Dr Qi Lei is the winner of this year’s Oden Institute Outstanding Dissertation Award.
  • Dr Lei is currently a postdoc research associate at Princeton University and plans to continue pursuing her interest in machine learning.

Read more

Media Coverage

Feb. 4, 2021

UT Austin researchers nab $3.8M from NASA to research unmanned aerial vehicles

Read more at bizjournals

UT Austin researchers receive $3.65 million from NASA to study drones’ impact on society

Media Coverage

Feb. 1, 2021

UT Austin researchers receive $3.65 million from NASA to study drones’ impact on society

  • NBC's local news outlet highlights NASA-funded research 

Read more at kxan

Unmanned Aerial Vehicles Scale New Heights

News

Jan. 21, 2021

Unmanned Aerial Vehicles Scale New Heights

  • Oden Institute plays leading role in NASA-funded research to scale unmanned aerial cargo transport
  • Computational modeling for scaling — from single delivery drone to large unmanned cargo aircraft

Read more

Machines Rise To The Grand Challenges of the 21st Century

News

Dec. 16, 2020

Machines Rise To The Grand Challenges of the 21st Century

Read more